8th February 2018
Optical images of dissolution of capsules with compositions highlighted in the figure showing (A-C) instantaneous, (D-E) sustained, pulsed and diffuse release. (F) High magnification images of the surface cracks of the capsule and (G) the emanating micron-sized nanoparticle clusters. (H) The droplet radius of the composite (D) capsule was found to remain approximately constant over time, and release of micron-sized nanoparticle clusters occurs in bursts, over long timescales, tuneable with pH. Copyright: Authors, taken without changes from 10.1126/sciadv.aao3353 which has been published under Creative Commons Licence CC BY 4.0 (https://creativecommons.org/licenses/by/4.0).

Nanocomposite Capsules with Directional, Pulsed Nanoparticle Release

The precise spatio-temporal delivery of nanoparticles from polymeric capsules is required for applications ranging from medicine to materials science. Reasearchers from the Imperial College London, UK, have demonstrated that microporosity and capsule morphology... (Read more)
8th February 2018
(a) Illustration of the different interaction mechanisms of the proteins, salt, and interface. (b) Sketch of protein adsorption on the attractive surface by increasing cs=cp. Copyright: Authors, reprinted with permission from DOI: 10.1103/PhysRevLett.119.228001.

Multivalent Ion-Activated Protein Adsorption Reflecting Bulk Reentrant Behavior

Protein adsorption at the solid-liquid interface is an important phenomenon that often can be observed as a first step in biological processes. A team from Germany and Great Britain has demonstrated the control... (Read more)
2nd July 2017
Finite element simulations show that a combination of convection and thermodiffusion enriches formamide in the pore (contour plot). The graph illustrates the accumulation normalized to the reservoir concentration ω_0 over time for different ω_0. The accumulation saturates around a formamide concentration of 85 wt%. The time necessary to reach the plateau τ_plateau depends on the reservoir concentration ω_0 (inset). Copyright: Forschungszentrum Jülich

Origin of Life: Accumulation of Formamide in Hydrothermal Pores to Form Prebiotic Nucleobases

One of the central questions of humankind is: which chemical and physical conditions are necessary to make life possible? In this “origin-of-life” context, formamide plays an important role, because it has been demonstrated... (Read more)
2nd July 2017
Large, temporary clusters lead to a dramatic slowdown in diffusion for patchy proteins. Copyright: Universität Lund

Dramatic Influence of Patchy Attractions on Short-Time Protein Diffusion under Crowded Conditions

Protein diffusion is pivotal for the functional properties of biological systems. Here we use quasielastic neutron scattering experiments combined with computer simulations to obtain quantitative information about the short-time diffusion of proteins in... (Read more)