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DTSTART;TZID=Europe/Berlin:20220408T080000
DTEND;TZID=Europe/Berlin:20220504T170000
DTSTAMP:20260526T163116
CREATED:20220422T074509Z
LAST-MODIFIED:20220422T074509Z
UID:4000-1649404800-1651683600@eu-softcomp.net
SUMMARY:Postdoc position at Lund University: Characterising concentrated antibody solutions
DESCRIPTION:We have an open postdoc position in the Division of Physical Chemistry at Lund University on the biophysical properties of antibody solutions and their investigation with a combination of scattering techniques and computer simulations. \nMonoclonal antibodies (mAbs) are engineered proteins that can serve as substitute antibodies in the immune system. Due to their high potential in e.g. cancer treatment they attract enormous attention from the pharmaceutical industry. At the same time the formulation of high concentration injectable mAb biologics is very challenging as it is often severely limited due to high turbidity and/or high viscosity. \nIn this project we aim at establishing an approach to understand the origin of this behaviour and to predict it from low concentration data and mAb molecular structure. The postdoc we are looking for will apply a variety of static and dynamic scattering techniques (based on light and x-rays) on mAb samples\, including static and dynamic light scattering (SLS/DLS)\, small-angle x-ray scattering (SAXS) and x-ray photon correlation spectroscopy (XPCS)\, and analyse the data. (S)he will also perform microrheology experiments\, establish mAb phase/state diagrams and closely work together with simulators and theoreticians in a concerted effort towards a better understanding of the complex solution behaviour of mAbs. \nRequirements are: \n\nPhD in Soft Matter Physics\, Biophysics\, Physical Chemistry or similar with a strong biophysical/biochemical background\,\nVery good oral and written proficiency in English\,\nExperience in protein and colloid science\,\nExperience in scattering techniques applied to soft and biological matter\,\nExperience in scattering data analysis\,\nExperience in collaboration with theoreticians and simulators\,\nExperience in protein sample preparation and handling.\n\nDeadline for application is 4 May 2022 \nMore information and a link for the on-line application can be found at: \nhttps://lu.varbi.com/en/what:job/jobID:494678/
URL:https://eu-softcomp.net/events/postdoc-position-at-lund-university-characterising-concentrated-antibody-solutions/
CATEGORIES:Job Opportunities
ORGANIZER;CN="Peter Schurtenberger":MAILTO:peter.schurtenberger@fkem1.lu.se
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DTSTART;TZID=Europe/Berlin:20220502T080000
DTEND;TZID=Europe/Berlin:20220731T170000
DTSTAMP:20260526T163116
CREATED:20220503T050131Z
LAST-MODIFIED:20220503T050131Z
UID:4062-1651478400-1659286800@eu-softcomp.net
SUMMARY:Tenure-track Junior Professor Chair : New materials and processes with low environmental impact
DESCRIPTION:Research project\nThe scientific project carried out by the Chair is at the intersection of the disciplinary fields of process and material sciences involving the use of supercritical fluids. It will allow the development of studies which will aim at : \n – Intensifying the adequacy between the process and the material by improving the process efficiency. It can be achieved by integrating several functions in a single operation and by reducing the consumption of inputs (monomers\, additives\, catalysts…). The idea is to optimize the physico-chemical properties and/or reactive systems by supercritical fluids as reagents or carrier fluids to provide new functions or as plasticizers to transform heat-sensitive materials such as biobased polymers. \n – Making the use of polymeric materials safer in order to increase their recycling towards currently unthinkable applications by achieving total clean-up/purification: offering ultra-pure virgin or recycled polymers\, \n – Continuously generating materials with properties that are different from those currently proposed: high-performance materials\, nano-cellular polymer foams or polymer blends with controlled morphologies. \nThe deployment of the scientific project relies on a base of existing projects currently composed of 3 PhD on recycling and 4 projects on the purification and development of cellular materials. As soon as he/she is recruited\, the person hired will be integrated into the follow-up of the projects. He/she will also supervise the doctoral and post-doctoral students recruited. They will be assigned to the development of the coupling of fluids under supercritical conditions and polymer processing and\, more particularly\, they will endeavour to associate conceptual aspects at different scales and states of matter with the experimental part (constitutive laws and scaling laws for complex polymer/supercritical fluids under strong flows\, fundamental mechanisms involved in the elaboration of nano-foams assisted by supercritical fluids\, understanding of the clean-up processes integrated in a recycling operation). \nThe overall budget allocated to the project amounts to 650000 € including salaries. \nContacts   Head of the lab : Pr Jean-Charles Majesté\, majeste@univ-st-etienne.fr \nHost laboratory:\nThe Laboratory « Ingénierie des Matériaux Polymères » (UMR CNRS 5223) is a research unit (70 senior scientists /130 Ph-D and postdocs) which focuses on polymer materials\, affiliated to CNRS\, University of Lyon\, INSA and to University Jean Monnet of Saint-Etienne). The laboratory has included in its roadmap the development of cross-disciplinary skills related to major societal challenges in both energy and environmental aspects\, including an approach to the development of materials with a virtuous life cycle. The person recruited at the Saint-Etienne site will be able to rely on the laboratory’s platform “FlusCritex” (unique in Europe) dedicated to the coupling of fluids under supercritical conditions and polymer processing. The development of this coupling approach requires the association of conceptual aspects at different scales and states of matter in addition to the experimental component. This conceptualization approach is an important research axis in the laboratory. \nTeaching project:\nThe person recruited as a tenure-track junior professor will be involved (64h/year) in the reinforcement of teaching on eco-design and the valorization of polymeric materials or their recycling\, which is one of the objectives of the new Master’s program “Chemistry and Materials Science”. The teaching project will thus participate in the more general dynamics within the establishment to develop the sustainable development and social responsibility theme in which the person recruited will be strongly involved\, for example in the design of opening and awareness units. \n 
URL:https://eu-softcomp.net/events/tenure-track-junior-professor-chair-new-materials-and-processes-with-low-environmental-impact/
CATEGORIES:Job Opportunities
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