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SoftComp e-Newsletter No. 5 - April 2025

Dear Members and Friends of SoftComp,

Since its inception in 2004, SoftComp has been at the forefront of promoting collaboration, innovation and progress in the faszinating interdisciplinary field of soft matter physics, chemistry and biology worldwide. The 20th anniversary of SoftComp last year is a significant milestone in the journey of our consortium. Through its conferences, workshops, publications and networking opportunities, SoftComp has played a crucial role over the past two decades in bringing together scientists, researchers and experts from diverse backgrounds to explore the fundamental properties and applications of soft materials. In addition, SoftComp has actively promoted education and outreach initiatives, inspiring the next generation of scientists to pursue careers in soft materials research. We are excited to continue following this successful path in the future.

Our sincere thanks go to all our supporters on this journey, which we will continue to pursue in the future!

Angela Wenzik & Stephan Förster
for the SoftComp Coordination, Management and Communication Team

Scientific News

Tricks from Ticks

Phase separation and ageing of glycine-rich protein

Fi. 1: Schematic illustrating the role of GRP phase transitions in the formation of the tick cement cone. Copyright: authors
Discover the fascinating world of tick adhesives! Researchers from SoftComp partner Wageningen University and Maastricht University, The Netherlands, have cracked the code on the mysterious liquid-to-solid transition of tick saliva, revealing new insights into bioadhesives. Learn how this breakthrough could lead to innovative tick control strategies and biomedical applications, from tissue sealants to medical sutures.

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Uncovering the Microscopic Origin of Fluidization

A unified state diagram for the yielding transition of soft colloids

Figure: Unified state diagram for the fluidization transition. For small deformation amplitudes, soft systems exhibit solid-like dynamics (blue points) with low fluidity, namely very large spontaneous relaxation times. As the deformation amplitude increases, soft systems undergo the fluidization transition (gray points), characterized by the coexistence of two types of dynamics (solid and fluid). They are eventually fluidized at very large deformations, where the microscopic dynamics resemble those of a liquid. (Copyright © 2023: the authors)
Scientists from the SoftComp partner CNRS Montpellier in France and the New York University, USA, have shed light on the microscopic origin of fluidization, a phenomenon where complex fluids transition from a solid-like state to a flowing state when subjected to external forces. The interpretation of the experimental results, which was inspired by the work of Dutch physicist J.D. van der Waals on phase transitions, opens doors to further research and potential innovations in fields such as materials science, engineering, and biotechnology.

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Electric Fields Shape Protein Crystal Formation

Figure: An optical microscopy image of lysozyme crystals in an electric field, with a view of 2x2 mm2. Courtesy of Dr. K. Kang, IBI-4, Forschungszentrum Jülich.
SoftComp partners from Forschungszentrum Jülich and Heinrich Heine University Düsseldorf, Germany, have uncovered the profound effects of electric fields on protein phase behaviour and crystallization. Their research offers valuable insights into how external electric fields can alter the behaviour of proteins at the molecular level.

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Unlocking Cell Secrets with Flicker Spectroscopy

Novel technique to measure properties of sub-cellular compartments

Figure 1: The formation of stress granules in human cells upon the addition of Sodium Arsenite. Green regions show the location of G3BP, a protein which is known to localise in stress granules. Scale bar: 20 μm. Copyright: Published in Law J. O. et. al., Sci. Adv., 9, eadg0432 (2023) under a Creative Commons Attribution 4.0 International License.
Scientists from SoftComp partner University of Durham, UK, and other European research institutes have developed a new technique to measure the properties of biomolecular condensates, shedding light on their role in cellular processes and diseases. Using Flicker Spectroscopy, the team analysed shape fluctuations in live cells, enabling the measurement of tens of thousands of condensates. Discover the implications of this innovative approach for our understanding of cellular biology.

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Upcycling Humins into Valuable Materials

Advancing sustainable materials development

Researchers at SoftComp's Belgian partner institution, KU Leuven, have developed a novel method for the upcycling of humins, a major by-product of biorefineries, into new materials. This addresses the challenges associated with the variable composition and handling properties of humins, and demonstrates their potential as building blocks for advanced bio-renewable materials, thus contributing to sustainable development and reduced reliance on fossil fuels.

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Biology Exploits Geometry

Impact of aspect ratio on protein network assembly

Scientists at SoftComp partner University of Leeds and STFC Rutherford Appleton Laboratory, UK, have made an exciting discovery about the functional advantages of high aspect ratio bio-polymers, found in nature's networks. These building blocks provide crucial structural and mechanical support, and can be engineered to create novel biomaterials.

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Event Reports

Annual Meeting 2024 Celebrated 20th Anniversary of SoftComp

129 SoftComp members and friends met from 21 to 24 May 2024 in Lyon for the SoftComp/EUSMI Annual Meeting 2024. It was dedicated to the special topic of sustainable soft matter. The festive setting was also used to celebrate the 20th anniversary of SoftComp. Meeting website

Four SoftComp Webinars Took Place in 2024

Four SoftComp webinars took place in 2024 and provided interesting insights into a wide range of research topics in the field of soft matter: Jacques Jestin from the ILL, France reported on ‘Soft Matter at the ILL’, Anthony Ryan from the University of Sheffield, United Kingdom on ‘From the Self-Assembly of Synthetic Soils to Growing Food in a Refugee Camp’. Norman Wagner from the University of Delaware, USA spoke in his webinar on ‘Novel Shear and Dilatational Interfacial Rheometer for the Study of Complex Fluids Applied to Polymers and mAbs at the Air-Water Interface’, Markus Antonietti from MPI Potsdam, Germany on ‘Carbon nitride: An Interface driven organic semiconductor and its use in artificial photosynthesis and photoosmotic machines’. The dates for 2025 will be announced gradually on the SoftComp website.

Intelligent Soft Matter Workshop with 64 Participants

The SoftComp Topical Workshop “Intelligent Soft Matter” has taken place from 26 to 29 September 2024 in Salou, Spain, and was organized by the Universitat Rovira i Virgili, Spain, the Forschungszentrum Jülich, Germany, and the Universita’ Ca’ Foscari, Italy. 64 participants attended 24 talks with the aim of jointly exploring ways to design new types of matter: Intelligent Soft Matter by combining the expertise and collaboration of the experts from three fields: active matter, decision making and nanosensors. One result of the workshop is an invited perspective article in the themed "Soft Matter 20th Anniversary Collection" of the journal Soft Matter. Workshop website

16th Bombannes Summer School Educated 42 Students

The 16th European Summer School on “Scattering Methods Applied to Soft Condensed Matter”, also known as the “Bombannes School”, was organised by the University of Montpellier and the ILL Grenoble, France, from 4 to 11 June 2024, and was once again sponsored by SoftComp, among others. School website

Upcoming Events

International Workshop on Advances in Mechanobiology: From Mechanical Sensing to Cell and Tissue Response
27 - 30 April 2025
Napoli, Italy

SoftComp/EUSMI Annual Meeting 2025
19 - 22 May 2025
Venice-Mestre, Italy

Higgs School on Advances in Computational Active Matter
29 June - 4 July 2025
University of Edinburgh, UK

Summer School on Polymeric Networks for Sustainable Development
6 - 12 July 2025
Capri, Italy

International Soft Matter Conference 2025
29 September - 3 October 2025
Chania, Crete, Greece

About SoftComp

SoftComp first emerged in 2004 as a Network of Excellence – a tool developed under the 6th Framework Programme of the European Commission – and continued as a self-sustaining Consortium in December 2009, when EU funding came to an end. SoftComp deals with the integration of European research, seeking to strengthen scientific and technological excellence in soft matter. In particular, it aims to establish a knowledge base for the intelligent design of functional and nanoscale soft matter composites, by overcoming the present fragmentation of this important field involved in the development of new materials at the interface of non-living and living matter, where the delicate principles of self-assembly in polymeric, surfactant and colloidal matter prevail. SoftComp has created an integrated team that is able to mobilize European potential in soft matter composite materials and thus disseminate excellence through extensive training and knowledge transfer schemes. Softcomp now consists of 36 research groups in 32 different institutions spread over 12 European countries.

Please visit our website for more information or to subscribe to our email newsletter: www.eu-softcomp.net/,
or get connected with us on Twitter: @SoftCompNetwork, and LinkedIn: SoftComp Consortium.
Archive of all SoftComp newsletters (electronic and print): Newsletters

Contact

Dr. Flavio Carsughi
SoftComp Project Manager
Forschungszentrum Jülich
JCNS Outstation
Lichtenbergstrasse 1
85748 Garching
Germany
Phone: + 49 89 289-10703
Fax: + 49 89 289-10799
Email: softcomp@fz-juelich.de
Angela Wenzik
SoftComp Newsletter Editor
Forschungszentrum Jülich GmbH
PGI/JCNS-TA
Administration
52425 Jülich
Germany
Phone: +49 2461 61-6048
Fax: +49 2461 61-2410
Email: softcomp@fz-juelich.de
Copyright of Images:
All scientific news images copyright authors besides “Unlocking Cell Secrets with Flicker Spectroscopy”, which has been published in Law J. O. et. al., Sci. Adv., 9, eadg0432 (2023) under a Creative Commons Attribution 4.0 International License.
Group image copyright SoftComp.
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